Spray drying involves the atomisation of a liquid feed into very small droplets within a hot drying gas. The feed can be a solution, a suspension, or an emulsion. The droplets dry very rapidly to become solid particles. The particles are then separated from the drying gas, using a cyclone or a filter bag, into a final spray dried powder product.
Spray drying reduces dosage costs, facilitates higher drug loading, and helps to extend product lifecycles. In addition, as a fast, efficient, and effective process, it also delivers a range of further benefits, including:
Our spray drying capabilities
With our state-of-the-art facilities and wide range of leading-edge spray drying technologies, we can support you throughout the whole lifecycle of your product, from toxicology studies and early clinical phases, to late clinical stage and commercial supply.
Our spray dryers can use either two-fluid, ultrasonic or high-pressure nozzles. We have also invested in the latest containment technology enabling us to work in high containment applications, managing high potent compounds (down to 30ng/m3).
All our spray dryers can handle aqueous and organic solvents and there are no limitations on the choice of solvent, including acetone, chloroform, dichloromethane, and THF.
Our spray drying equipment includes:
Further secondary drying is possible in our static and dynamic vacuum dryers, both small and large scale.
Our state-of-the-art facilities and technologies mean we have the capacity and potential to give you full spray drying scale up from clinical trials to commercial supply when your project needs it.
All clinical trial manufacturing and commercial manufacturing is performed in accordance with (cGMP), with release approved by a Qualified Person (QP).
Would you like to know more about how Micro-Sphere can help with your next project? Get in touch to learn more about our services, experience and expertise.Contact
We provide a range of specialist pharmaceutical contract manufacturing services in the spray drying of aqueous and organic solutions, of conventional APIs, HPAPIs, lipids, proteins, and in capsule filling for dry powder.View Services