Your reliable partner for spray drying
Micro-Sphere S.A. is a contract development and manufacturing organisation (CDMO) with specialist expertise in the spray drying of APIs and HPAPIs.
Founded in 1998, we have a long track record in overcoming complex formulation challenges and then taking products from development batches to Phase II and beyond.
From our facility in Switzerland, our 40-strong team deliver both clinical and commercial scale spray drying and capsule filling services, helping pharmaceutical companies across the globe to advance drug development and bring new products to market.
Micro-Sphere has specialist expertise in spray drying of aqueous and organic solutions, conventional APIs, HPAPIs, proteins, and capsule filling for dry powder inhalation.
Our range of services include:
- Spray drying (GEA Niro)
- Spray chilling (GEA Niro)
- Capsule filling (Harro Höfliger, MG2)
- Nano-emulsion and liposomes
- Analytical services for dry powder inhalable (DUSA, NGI, MSLI, ACI)
- Analytical services for engineered particles (PSD, SEM)
- Technology transfer
- Project management
Whether your project requirement is at a clinical or commercial scale, our team can help.
As demand for GMP spray drying grows globally, we recognise the industry-wide need for high quality, flexible contract services.
Our expert team supports customers in North America, Europe, Asia and Oceania with demanding projects involving complex formulation challenges.
Due to our primary focus on spray drying, we have the expertise to support you with the development and manufacture of both potent and non-potent pharmaceutical products at clinical and commercial scale.
Our spray drying services include:
- Spray drying to process amorphous products as well as to
isolate APIs from organic solvent
- Formulation of APIs and HPAPIs with a particular interest
in the field of pulmonary delivery
- Formulation of molecules with poor bioavailability in
liposomes and nano-emulsions by the technique of high
pressure homogenisation with subsequent spray drying
- Spray drying of solid dispersions
Technical expertise combined with quality systems and compliance.
Our state-of-the-art facility is specifically designed for spray drying and capsule filling. This means we can provide the flexibility needed to meet your project requirements and timescales.
We understand that quality and compliance are important to you when engaging with contract partners. Our customers tell us that our facility provides an unparalleled level of quality, and we have the compliance track record to prove it. Our EU GMP, FDA and SwissMedic approved facility boasts big pharma standard quality systems and infrastructure.
Our facility is home to some of the world’s leading spray drying and capsule filling technologies.
In 2017, we invested 21 million CHF (€19 million) into our GMP manufacturing capabilities. The investment, which tripled the size of our production area, means we have the capacity to handle larger quantities of pharmaceutical powders and commercial volumes of finished dosage forms.